OK, the Lion Brand Homespun. I *have* worked with that, at least in its regular weight, and the only way I could get it to behave was to double-strand it with a worsted and use size 15s (10 mm).
For a table runner, though, the double-stranding would be awfully thick; I was making a neck scarf for a community service project where protection from the cold is paramount. Is the table runner just for deco, or will tableware be placed on it? If it's too thick, the tableware will probably wobble on the double-stranding....