Yes, when you start working the other direction, the sts are offset half a stitch. But if it's plain stockinette or garter it won't matter. If it's garter stitch make sure the purl bumps are facing you on the left needle to keep in the garter stitch pattern. If the knits are on the left, then you can purl the row instead of knit it and it'll stay garter stitch.
sue- knitting heretic