I do toe-up. I don't like to do Kitchener stitch and I know how much yarn it takes to make a sock but I'm afraid of running out because I used too much on the cuff. I keep thinking I should look at some books but so far have just done the Lifestyle Sock thing, no swatch, make to fit. I want to try some mini cables on my next pair so I've been playing with twisted stitches. I think there is some kind of reinforcing yarn you can use but I'm not sure. I need go google and see what I can find out. Right now I'm working on a shawl I need to get done, a google break sounds like a good idea.
Size 1 needles, that's what I used last time and ended up with 000 dpns to do the cuff.