I am a cuff to toe girl, just because that is what I've done and am most comfortable with. I admit it (hangs head) I've not yet tried toe to cuff, but I am, I promise, as soon as I'm done with A Touch of Whimsy socks, the next ones will be toe up
As for a preference, I would say it's all in what you are used to, like me

I know you will enjoy toe to cuff just as much as cuff to toe because it's socknitting and all socknitting is fun
