You can, as its really only one thickness up.
You'll need to do a gauge swatch. Depending on what you are making, you may need to use one size larger needle to maintain the desired drape (mostly for clothing). This will create a larger object so you may need to make a smaller size (for clothing) or cast on fewer repeats (blanket) to get the desired size.
Last edited by RochesterKnitter : 10-18-2013 at 07:01 PM.