Best bet is to open the hank to a big circle and lay it around two chairbacks and take a lenghth of it off and make a center pull ball (amy has a video on that), or have a patient friend hold the opened hank around their hands.
DON'T TRY TO KNIT FROM A HANK...YOU'LL BE VERY SORRY!!!!
This topic's been addressed a lot so do a search and I bet you'l find a lot of tips. If possible, take it to your LYS if you have one and see if they would wind it for you, no headache!