OH yeah, dusti, you can do that with whatever pattern. If you find any pattern that you like, you can easily just knit the pattern on the leg and change to st st for the foot, afterall, really, who is gonna see the foot?!
Or, if you have a st pattern that you really like it's easy to transform it to knitting in the round and use it on the leg of your socks...socknitting is pretty much limited by your imagination! You can do so many things with socks, I get all knitty excited just thinking about it