I took a quick look at the Ayla Pattern, and it calls for just one strand of Cascade 220 to be knitted up on 10 1/2s. Malabrigo is thicker, plus you have another strand of yarn held with it. So the 13s or 15s are a good choice. I'm working on a to-be-felted cat bed (Kitty Pi) with Lamb's Pride scraps...I'm using 13s and one strand of Bulky or double-stranded worsted.
Ariann Cardigan in Brown Sheep Cotton Fleece - 11 inches and two buttonholes done!
Tomato from No Sheep for You in Cotton Ease - nearly done! One sleeve left.
Tuscany from NSFY in Elsebeth Lavold Silky Wool - it's working up beautifully.
Montego Bay Scarf from Summer 07 IK Knits in Sea Silk - an indulgent knit